Use of nonionic or low osmolar contrast agents in cardiovascular procedures

Renal failure in 57 925 patients undergoing coronary procedures using iso-osmolar or low-osmolar contrast media.

We compared the Swedish Coronary Angiography and Angioplasty Registry with the Swedish 'Hospital Discharge Register' to assess contrast media (CM)-induced renal failure. Hospitals used only one type CM. From 2000 to 2003, iodixanol (iso-osmolar) was used in 45 485 patients, ioxaglate (low osmolar) in 12 440 subjects. To include the earlier used CM iohexol (low osmolar), analysis extended back t...

Contrast nephropathy: isosmolar and low-osmolar contrast media.

1. Hurst RT, Askew JW, Reuss CS, et al. Transient midventricular ballooning syndrome: a new variant. J Am Coll Cardiol 2006;48: 579 – 83. 2. Sharkey SW, Lesser JR, Zenovich AG, et al. Acute and reversible cardiomyopathy provoked by stress in women from the United States. Circulation 2005;111:472–9. 3. Abdulla I, Kay S, Mussap C, et al. Apical sparing in tako-tsubo cardiomyopathy. Intern Med J 2...

&C POSITION STATEMENT Use of ~onionic or Cardiovascular ~~~~ed~res AMERICAN COLLEGE OF CARDIOLOGY CARDIOVASCULAR IMAGlNG COMMITTEE”

lodinated radiopaque contrast agents are utilized in many of the approximately I million or more cardiac carherenzalions performed each year in the United States. Until recently. the primary agents employed for cardiovascular imaging consisted of diatrizoate sodium or a combination of diatrizoate sodium and various m&urdne salts. These agents are referred to as “ionic” or “idgh osmolar” agent> ...

Iso-Osmolar versus Low-Osmolar Contrast Media in Reducing Contrast Induced Nephropathy in Patient with Renal Impairment Undergoing Coronary Angiography

Use of ultrasound contrast agents for gene or drug delivery in cardiovascular medicine.

The clinical utility of ultrasound contrast agents has been established in diagnostic echocardiography. Recently, the use of such agents has been promoted for transport and delivery of various bioactive substances, thus providing a technique for non-invasive gene therapy and organ-specific drug delivery. In this review, we give a critical update of published studies using ultrasound contrast ag...